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Membrane binding of the insertion sequence of Proteus vulgaris L-amino acid deaminase stabilizes protein structure and increases catalytic activity

Proteus vulgaris L-amino acid deaminase (pvLAAD) belongs to a class of bacterial membrane-bound LAADs mainly express in genus Proteus, Providencia and Morganella. These LAADs employ a non-cleavable N-terminal twin-arginine translocation (Tat) peptide to transport across membrane and bind to bacteria...

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Detalles Bibliográficos
Autores principales: Ju, Yingchen, Liu, Zhihong, Zhang, Zizhen, Duan, Lijun, Liu, Qi, Gu, Qiong, Zhang, Cheng, Xu, Jun, Zhou, Huihao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651824/
https://www.ncbi.nlm.nih.gov/pubmed/29057984
http://dx.doi.org/10.1038/s41598-017-14238-7