Paraquat and MPTP induce neurodegeneration and alteration in the expression profile of microRNAs: the role of transcription factor Nrf2

Both transcription factors (TFs) and microRNAs (miRNAs) can exert a widespread impact on gene expression. In the present study, we investigated the role of Nrf2 in paraquat-induced intracorporeal neurodegeneration and miRNA expression by exposing Nrf2 wild-type and knockout mice to paraquat (PQ) or...

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Detalles Bibliográficos
Autores principales: Wang, Qingqing, Ren, Nan, Cai, Zhipeng, Lin, Qingxia, Wang, Zhangjing, Zhang, Qunwei, Wu, Siying, Li, Huangyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651826/
https://www.ncbi.nlm.nih.gov/pubmed/29071302
http://dx.doi.org/10.1038/s41531-017-0033-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651826/
https://www.ncbi.nlm.nih.gov/pubmed/29071302
http://dx.doi.org/10.1038/s41531-017-0033-1

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