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A New Generation of Arachidonic Acid Analogues as Potential Neurological Agent Targeting Cytosolic Phospholipase A(2)

Cytosolic phospholipase A(2) (cPLA(2)) is an enzyme that releases arachidonic acid (AA) for the synthesis of eicosanoids and lysophospholipids which play critical roles in the initiation and modulation of oxidative stress and neuroinflammation. In the central nervous system, cPLA(2) activation is im...

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Detalles Bibliográficos
Autores principales: Ng, Cheng Yang, Kannan, Srinivasaraghavan, Chen, Yong Jun, Tan, Francis Chee Kuan, Ong, Wee Yong, Go, Mei Lin, Verma, Chandra S., Low, Chian-Ming, Lam, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651845/
https://www.ncbi.nlm.nih.gov/pubmed/29057981
http://dx.doi.org/10.1038/s41598-017-13996-8