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A New Generation of Arachidonic Acid Analogues as Potential Neurological Agent Targeting Cytosolic Phospholipase A(2)
Cytosolic phospholipase A(2) (cPLA(2)) is an enzyme that releases arachidonic acid (AA) for the synthesis of eicosanoids and lysophospholipids which play critical roles in the initiation and modulation of oxidative stress and neuroinflammation. In the central nervous system, cPLA(2) activation is im...
Autores principales: | Ng, Cheng Yang, Kannan, Srinivasaraghavan, Chen, Yong Jun, Tan, Francis Chee Kuan, Ong, Wee Yong, Go, Mei Lin, Verma, Chandra S., Low, Chian-Ming, Lam, Yulin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651845/ https://www.ncbi.nlm.nih.gov/pubmed/29057981 http://dx.doi.org/10.1038/s41598-017-13996-8 |
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