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R/G editing in GluA2R(flop) modulates the functional difference between GluA1 flip and flop variants in GluA1/2R heteromeric channels

In α-amino-3-hydroxy-5-methyl-4-isoxazole-propionate (AMPA) receptors, RNA editing and alternative splicing generate sequence variants, and those variants, as in GluA2-4 AMPA receptor subunits, generally show different properties. Yet, earlier studies have shown that the alternatively spliced, flip...

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Detalles Bibliográficos
Autores principales: Wen, Wei, Lin, Chi-Yen, Niu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651858/
https://www.ncbi.nlm.nih.gov/pubmed/29057893
http://dx.doi.org/10.1038/s41598-017-13233-2