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Myosin X is recruited to nascent focal adhesions at the leading edge and induces multi-cycle filopodial elongation
Filopodia protrude from the leading edge of cells and play important roles in cell motility. Here we report the mechanism of myosin X (encoded by Myo10)-induced multi-cycle filopodia extension. We found that actin, Arp2/3, vinculin and integrin-β first accumulated at the cell’s leading edge. Myosin...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651867/ https://www.ncbi.nlm.nih.gov/pubmed/29057977 http://dx.doi.org/10.1038/s41598-017-06147-6 |