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Myosin X is recruited to nascent focal adhesions at the leading edge and induces multi-cycle filopodial elongation

Filopodia protrude from the leading edge of cells and play important roles in cell motility. Here we report the mechanism of myosin X (encoded by Myo10)-induced multi-cycle filopodia extension. We found that actin, Arp2/3, vinculin and integrin-β first accumulated at the cell’s leading edge. Myosin...

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Detalles Bibliográficos
Autores principales:	He, Kangmin, Sakai, Tsuyoshi, Tsukasaki, Yoshikazu, Watanabe, Tomonobu M., Ikebe, Mitsuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651867/ https://www.ncbi.nlm.nih.gov/pubmed/29057977 http://dx.doi.org/10.1038/s41598-017-06147-6

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