Identification and Validation of a PD-L1 Binding Peptide for Determination of PDL1 Expression in Tumors

Blocking the interaction between Programmed Death Ligand 1 (PD-L1) and its receptor, PD-1, is an effective method of treating many types of cancers. Certain tumors overexpress PD-L1, causing host immune cells that express PD-1 to bind PD-L1 and cease killing the tumor. Inhibition of PD-L1 and PD-1 b...

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Detalles Bibliográficos
Autores principales: Caldwell, Charles, Johnson, Cory E., Balaji, V. N., Balaji, Govardhan A., Hammer, Richard D., Kannan, Raghuraman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651871/
https://www.ncbi.nlm.nih.gov/pubmed/29057919
http://dx.doi.org/10.1038/s41598-017-10946-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651871/
https://www.ncbi.nlm.nih.gov/pubmed/29057919
http://dx.doi.org/10.1038/s41598-017-10946-2

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