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Identification and Validation of a PD-L1 Binding Peptide for Determination of PDL1 Expression in Tumors
Blocking the interaction between Programmed Death Ligand 1 (PD-L1) and its receptor, PD-1, is an effective method of treating many types of cancers. Certain tumors overexpress PD-L1, causing host immune cells that express PD-1 to bind PD-L1 and cease killing the tumor. Inhibition of PD-L1 and PD-1 b...
Autores principales: | Caldwell, Charles, Johnson, Cory E., Balaji, V. N., Balaji, Govardhan A., Hammer, Richard D., Kannan, Raghuraman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651871/ https://www.ncbi.nlm.nih.gov/pubmed/29057919 http://dx.doi.org/10.1038/s41598-017-10946-2 |
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