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Silencing Nfix rescues muscular dystrophy by delaying muscle regeneration

Muscular dystrophies are severe disorders due to mutations in structural genes, and are characterized by skeletal muscle wasting, compromised patient mobility, and respiratory functions. Although previous works suggested enhancing regeneration and muscle mass as therapeutic strategies, these led to...

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Detalles Bibliográficos
Autores principales: Rossi, Giuliana, Bonfanti, Chiara, Antonini, Stefania, Bastoni, Mattia, Monteverde, Stefania, Innocenzi, Anna, Saclier, Marielle, Taglietti, Valentina, Messina, Graziella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651883/
https://www.ncbi.nlm.nih.gov/pubmed/29057908
http://dx.doi.org/10.1038/s41467-017-01098-y