Cargando…
Silencing Nfix rescues muscular dystrophy by delaying muscle regeneration
Muscular dystrophies are severe disorders due to mutations in structural genes, and are characterized by skeletal muscle wasting, compromised patient mobility, and respiratory functions. Although previous works suggested enhancing regeneration and muscle mass as therapeutic strategies, these led to...
Autores principales: | Rossi, Giuliana, Bonfanti, Chiara, Antonini, Stefania, Bastoni, Mattia, Monteverde, Stefania, Innocenzi, Anna, Saclier, Marielle, Taglietti, Valentina, Messina, Graziella |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651883/ https://www.ncbi.nlm.nih.gov/pubmed/29057908 http://dx.doi.org/10.1038/s41467-017-01098-y |
Ejemplares similares
-
Targeting Nfix to fix muscular dystrophies
por: Rossi, Giuliana, et al.
Publicado: (2017) -
The Transcription Factor Nfix Requires RhoA-ROCK1 Dependent Phagocytosis to Mediate Macrophage Skewing during Skeletal Muscle Regeneration
por: Saclier, Marielle, et al.
Publicado: (2020) -
Selective ablation of Nfix in macrophages attenuates muscular dystrophy by inhibiting fibro‐adipogenic progenitor‐dependent fibrosis
por: Saclier, Marielle, et al.
Publicado: (2022) -
Nfix Regulates Temporal Progression of Muscle Regeneration through Modulation of Myostatin Expression
por: Rossi, Giuliana, et al.
Publicado: (2016) -
Nutritional intervention with cyanidin hinders the progression of muscular dystrophy
por: Saclier, Marielle, et al.
Publicado: (2020)