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Glioblastoma cancer stem cell lines express functional acid sensing ion channels ASIC1a and ASIC3
Acidic microenvironment is commonly observed in tumour tissues, including glioblastoma (GBM), the most aggressive and lethal brain tumour in adults. Acid sensing ion channels (ASICs) are neuronal voltage-insensitive sodium channels, which are sensors of extracellular protons. Here we studied and fun...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651884/ https://www.ncbi.nlm.nih.gov/pubmed/29057936 http://dx.doi.org/10.1038/s41598-017-13666-9 |