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Glioblastoma cancer stem cell lines express functional acid sensing ion channels ASIC1a and ASIC3

Acidic microenvironment is commonly observed in tumour tissues, including glioblastoma (GBM), the most aggressive and lethal brain tumour in adults. Acid sensing ion channels (ASICs) are neuronal voltage-insensitive sodium channels, which are sensors of extracellular protons. Here we studied and fun...

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Detalles Bibliográficos
Autores principales: Tian, Yuemin, Bresenitz, Pia, Reska, Anna, El Moussaoui, Laila, Beier, Christoph Patrick, Gründer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651884/
https://www.ncbi.nlm.nih.gov/pubmed/29057936
http://dx.doi.org/10.1038/s41598-017-13666-9