MKL1 expressed in macrophages contributes to the development of murine colitis

Mice deficient in the megakaryoblastic leukaemia 1 (Mkl1) gene experience less severe dextran sulphate sodium (DSS)-induced colitis, implying that Mkl1 plays a pathological role in inflammatory bowel disease (IBD). However, the contribution of Mkl1 to the development of colitis remains to be elucida...

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Detalles Bibliográficos
Autores principales: An, Jianbo, Nagaishi, Takashi, Watabe, Taro, Naruse, Taeko K., Watanabe, Mamoru, Kimura, Akinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651926/
https://www.ncbi.nlm.nih.gov/pubmed/29057966
http://dx.doi.org/10.1038/s41598-017-13629-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651926/
https://www.ncbi.nlm.nih.gov/pubmed/29057966
http://dx.doi.org/10.1038/s41598-017-13629-0

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