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Follicular Helper T Cells are Essential for the Elimination of Plasmodium Infection

CD4(+) follicular helper T (Tfh) cells have been shown to be critical for the activation of germinal center (GC) B-cell responses. Similar to other infections, Plasmodium infection activates both GC as well as non-GC B cell responses. Here, we sought to explore whether Tfh cells and GC B cells are r...

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Detalles Bibliográficos
Autores principales: Pérez-Mazliah, Damián, Nguyen, Minh Phuong, Hosking, Caroline, McLaughlin, Sarah, Lewis, Matthew D., Tumwine, Irene, Levy, Prisca, Langhorne, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652023/
https://www.ncbi.nlm.nih.gov/pubmed/28888925
http://dx.doi.org/10.1016/j.ebiom.2017.08.030