IRX3 Promotes the Browning of White Adipocytes and Its Rare Variants are Associated with Human Obesity Risk

BACKGROUND: IRX3 was recently reported as the effector of the FTO variants. We aimed to test IRX3's roles in the browning program and to evaluate the association between the genetic variants in IRX3 and human obesity. METHODS: IRX3 expression was examined in beige adipocytes in human and mouse...

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Detalles Bibliográficos
Autores principales: Zou, Yaoyu, Lu, Peng, Shi, Juan, Liu, Wen, Yang, Minglan, Zhao, Shaoqian, Chen, Na, Chen, Maopei, Sun, Yingkai, Gao, Aibo, Chen, Qingbo, Zhang, Zhiguo, Ma, Qinyun, Ning, Tinglu, Ying, Xiayang, Jin, Jiabin, Deng, Xiaxing, Shen, Baiyong, Zhang, Yifei, Yuan, Bo, Kauderer, Sophie, Liu, Simin, Hong, Jie, Liu, Ruixin, Ning, Guang, Wang, Weiqing, Gu, Weiqiong, Wang, Jiqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652024/
https://www.ncbi.nlm.nih.gov/pubmed/28988979
http://dx.doi.org/10.1016/j.ebiom.2017.09.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652024/
https://www.ncbi.nlm.nih.gov/pubmed/28988979
http://dx.doi.org/10.1016/j.ebiom.2017.09.010

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