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Characterization of a New Allelic Variant of Triosephosphate Isomerase from the LNCaP Human Prostate Cancer Cell Line: Enzyme Inhibition and Spectroscopic Studies

BACKGROUND: The glycolytic pathway plays an important role in tumor cells. Triosephosphate isomerase (TIM) catalyzes the reversible isomerization of D-glyceraldehyde-3-phosphate (GAP) to dihydroxyacetone phosphate (DHAP) in the glycolysis. Proteomics of a human prostate adenocarcinoma cell line reve...

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Detalles Bibliográficos
Autores principales: Guzmán-Luna, Valeria, Olvera-Rodríguez, Leticia, Bustamante-Villalobos, Peniel, Saab-Rincón, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652080/
https://www.ncbi.nlm.nih.gov/pubmed/29123462
http://dx.doi.org/10.2174/1573408012666160906110330