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Antihypertrophic Effects of Small Molecules that Maintain Mitochondrial ATP Levels Under Hypoxia

Since impaired mitochondrial ATP production in cardiomyocytes is thought to lead to heart failure, a drug that protects mitochondria and improves ATP production under disease conditions would be an attractive treatment option. In this study, we identified small-molecule drugs, including the anti-par...

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Detalles Bibliográficos
Autores principales: Nagai, Hiroaki, Satomi, Tomoko, Abiru, Akiko, Miyamoto, Kazumasa, Nagasawa, Koji, Maruyama, Minoru, Yamamoto, Satoshi, Kikuchi, Kuniko, Fuse, Hiromitsu, Noda, Masakuni, Tsujihata, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652136/
https://www.ncbi.nlm.nih.gov/pubmed/28942281
http://dx.doi.org/10.1016/j.ebiom.2017.09.022