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Antihypertrophic Effects of Small Molecules that Maintain Mitochondrial ATP Levels Under Hypoxia
Since impaired mitochondrial ATP production in cardiomyocytes is thought to lead to heart failure, a drug that protects mitochondria and improves ATP production under disease conditions would be an attractive treatment option. In this study, we identified small-molecule drugs, including the anti-par...
Autores principales: | Nagai, Hiroaki, Satomi, Tomoko, Abiru, Akiko, Miyamoto, Kazumasa, Nagasawa, Koji, Maruyama, Minoru, Yamamoto, Satoshi, Kikuchi, Kuniko, Fuse, Hiromitsu, Noda, Masakuni, Tsujihata, Yoshiyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652136/ https://www.ncbi.nlm.nih.gov/pubmed/28942281 http://dx.doi.org/10.1016/j.ebiom.2017.09.022 |
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