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Lentivirus-mediated RNA interference inhibits the tumorigenicity of cluster of differentiation 44(+) tumor cells in hypopharyngeal cancer

The present study aimed to investigate whether the inhibition of cluster of differentiation (CD)44 expression reduces the tumorigenicity of CD44(+) cancer stem cells in hypopharyngeal cancer. To assess this, effective recombinant CD44 short hairpin RNA-expressing lentiviruses were produced. Lentivir...

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Detalles Bibliográficos
Autores principales: Shen, Chenling, Ye, Bin, Hu, Haixia, Nie, Chen, Ma, Yan, Lv, Jingrong, Wu, Hao, Xiang, Mingliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652143/
https://www.ncbi.nlm.nih.gov/pubmed/29113169
http://dx.doi.org/10.3892/ol.2017.6838