Pyrrolidine dithiocarbamate sensitizes U251 brain glioma cells to temozolomide via downregulation of MGMT and BCL-XL

The current study investigated the effect of pyrrolidine dithiocarbamate (PDTC) on the proliferation, apoptosis, cell cycle and sensitivity to temozolomide (TMZ) of the U251 glioma cell line. Proliferation, apoptosis and cell cycle analysis of U251 cells following treatment with PDTC and TMZ was det...

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Detalles Bibliográficos
Autores principales: Tang, Jun-Hai, Huang, Guo-Hao, Mou, Ke-Jie, Zhang, Eric Erquan, Li, Ningning, Du, Lei, Zhu, Xiao-Peng, Chen, Ling, Yang, Hui, Zhang, Ke-Bin, Lv, Sheng-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652242/
https://www.ncbi.nlm.nih.gov/pubmed/29098021
http://dx.doi.org/10.3892/ol.2017.6849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652242/
https://www.ncbi.nlm.nih.gov/pubmed/29098021
http://dx.doi.org/10.3892/ol.2017.6849

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