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Therapeutic effects of protein kinase N3 small interfering RNA and doxorubicin combination therapy on liver and lung metastases

It has been reported that suppression of protein kinase N3 (PKN3) expression in vascular and lymphatic endothelial cells results in the inhibition of tumor progression and lymph node metastasis formation. The present study investigated whether combination therapy of small interfering RNA (siRNA) aga...

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Detalles Bibliográficos
Autores principales: Hattori, Yoshiyuki, Kikuchi, Takuto, Nakamura, Mari, Ozaki, Kei-Ichi, Onishi, Hiraku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652245/
https://www.ncbi.nlm.nih.gov/pubmed/29098022
http://dx.doi.org/10.3892/ol.2017.6830