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Cell-Mediated Immune Predictors of Vaccine Effect on Viral Load and CD4 Count in a Phase 2 Therapeutic HIV-1 Vaccine Clinical Trial

BACKGROUND: In a placebo-controlled trial of the peptide-based therapeutic HIV-1 p24(Gag) vaccine candidate Vacc-4x, participants on combination antiretroviral therapy (cART) received six immunizations over 18 weeks, followed by analytical treatment interruption (ATI) between weeks 28 and 52. Cell-m...

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Detalles Bibliográficos
Autores principales: Huang, Yunda, Pantaleo, Giuseppe, Tapia, Gonzalo, Sanchez, Brittany, Zhang, Lily, Trondsen, Monica, Hovden, Arnt-Ove, Pollard, Richard, Rockstroh, Jürgen, Ökvist, Mats, Sommerfelt, Maja A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652289/
https://www.ncbi.nlm.nih.gov/pubmed/28970080
http://dx.doi.org/10.1016/j.ebiom.2017.09.028