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Cell-Mediated Immune Predictors of Vaccine Effect on Viral Load and CD4 Count in a Phase 2 Therapeutic HIV-1 Vaccine Clinical Trial
BACKGROUND: In a placebo-controlled trial of the peptide-based therapeutic HIV-1 p24(Gag) vaccine candidate Vacc-4x, participants on combination antiretroviral therapy (cART) received six immunizations over 18 weeks, followed by analytical treatment interruption (ATI) between weeks 28 and 52. Cell-m...
Autores principales: | Huang, Yunda, Pantaleo, Giuseppe, Tapia, Gonzalo, Sanchez, Brittany, Zhang, Lily, Trondsen, Monica, Hovden, Arnt-Ove, Pollard, Richard, Rockstroh, Jürgen, Ökvist, Mats, Sommerfelt, Maja A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652289/ https://www.ncbi.nlm.nih.gov/pubmed/28970080 http://dx.doi.org/10.1016/j.ebiom.2017.09.028 |
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