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Gestation age dependent transfer of human immunoglobulins across placenta in timed-pregnant guinea pigs

INTRODUCTION: When administered during pregnancy, antibodies and other biologic drugs that contain the Fc part of the IgG molecule can traverse the placenta. Although it is generally accepted that the FcRn receptor mediates this process, gaps remain in our understanding of underlying details in huma...

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Detalles Bibliográficos
Autores principales: Xu, Yanqun, Ma, Li, Norton, Malgorzata G., Stuart, Christine, Zhao, Zhong, Toibero, Denise, Dahlen, Shelby, Zhong, Lilin, Zhang, Pei, Struble, Evi B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652295/
https://www.ncbi.nlm.nih.gov/pubmed/26578159
http://dx.doi.org/10.1016/j.placenta.2015.10.018