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Gestation age dependent transfer of human immunoglobulins across placenta in timed-pregnant guinea pigs
INTRODUCTION: When administered during pregnancy, antibodies and other biologic drugs that contain the Fc part of the IgG molecule can traverse the placenta. Although it is generally accepted that the FcRn receptor mediates this process, gaps remain in our understanding of underlying details in huma...
Autores principales: | Xu, Yanqun, Ma, Li, Norton, Malgorzata G., Stuart, Christine, Zhao, Zhong, Toibero, Denise, Dahlen, Shelby, Zhong, Lilin, Zhang, Pei, Struble, Evi B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652295/ https://www.ncbi.nlm.nih.gov/pubmed/26578159 http://dx.doi.org/10.1016/j.placenta.2015.10.018 |
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