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High-Level Fosfomycin Resistance in Vancomycin-Resistant Enterococcus faecium

Of 890 vancomycin-resistant Enterococcus faecium isolates obtained by rectal screening from patients in Pittsburgh, Pennsylvania, USA, 4 had MICs >1,024 μg/mL for fosfomycin. These isolates had a Cys119Asp substitution in the active site of UDP-N-acetylglucosamine enolpyruvyl transferase. This su...

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Detalles Bibliográficos
Autores principales: Guo, Yan, Tomich, Adam D., McElheny, Christi L., Cooper, Vaughn S., Tait-Kamradt, Amelia, Wang, Minggui, Hu, Fupin, Rice, Louis B., Sluis-Cremer, Nicolas, Doi, Yohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652432/
https://www.ncbi.nlm.nih.gov/pubmed/29048285
http://dx.doi.org/10.3201/eid2311.171130