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Association between malignancies and Marfan syndrome: a population-based, nested case–control study in Taiwan
OBJECTIVE: Marfan syndrome (MFS) involves a deficiency of the structural extracellular matrix component fibrillin-1 and overactivation of the transforming growth factor-β (TGF-β) signalling pathway. The TGF-β signalling pathway also actively participates in malignant transformation. Although anecdot...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652471/ https://www.ncbi.nlm.nih.gov/pubmed/29042385 http://dx.doi.org/10.1136/bmjopen-2017-017243 |