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Age-dependent atrial arrhythmic phenotype secondary to mitochondrial dysfunction in Pgc-1β deficient murine hearts

INTRODUCTION: Ageing and several age-related chronic conditions including obesity, insulin resistance and hypertension are associated with mitochondrial dysfunction and represent independent risk factors for atrial fibrillation (AF). MATERIALS AND METHODS: Atrial arrhythmogenesis was investigated in...

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Detalles Bibliográficos
Autores principales: Valli, Haseeb, Ahmad, Shiraz, Chadda, Karan R., Al-Hadithi, Ali B.A.K., Grace, Andrew A., Jeevaratnam, Kamalan, Huang, Christopher L.-H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ireland 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652526/
https://www.ncbi.nlm.nih.gov/pubmed/28919427
http://dx.doi.org/10.1016/j.mad.2017.09.002