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Hepatic GALE Regulates Whole-Body Glucose Homeostasis by Modulating Tff3 Expression

Transcripts of key enzymes in the Leloir pathway of galactose metabolism in mouse livers are significantly increased after chronic high-fat/high-sucrose feeding. UDP-galactose-4-epimerase (GALE) is the last enzyme in this pathway that converts UDP-galactose to UDP-glucose and was previously identifi...

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Detalles Bibliográficos
Autores principales: Zhu, Yi, Zhao, Shangang, Deng, Yingfeng, Gordillo, Ruth, Ghaben, Alexandra L., Shao, Mengle, Zhang, Fang, Xu, Ping, Li, Yang, Cao, Huachuan, Zagnitko, Olga, Scott, David A., Gupta, Rana K., Xing, Chao, Zhang, Bei B., Lin, Hua V., Scherer, Philipp E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652600/
https://www.ncbi.nlm.nih.gov/pubmed/28877911
http://dx.doi.org/10.2337/db17-0323