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A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes
Type 2 diabetes (T2D) affects more than 415 million people worldwide, and its costs to the health care system continue to rise. To identify common or rare genetic variation with potential therapeutic implications for T2D, we analyzed and replicated genome-wide protein coding variation in a total of...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652606/ https://www.ncbi.nlm.nih.gov/pubmed/28838971 http://dx.doi.org/10.2337/db17-0187 |