Defining a Novel Role for the Pdx1 Transcription Factor in Islet β-Cell Maturation and Proliferation During Weaning

The transcription factor encoded by the Pdx1 gene is a critical transcriptional regulator, as it has fundamental actions in the formation of all pancreatic cell types, islet β-cell development, and adult islet β-cell function. Transgenic- and cell line–based experiments have identified 5′-flanking c...

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Detalles Bibliográficos
Autores principales: Spaeth, Jason M., Gupte, Manisha, Perelis, Mark, Yang, Yu-Ping, Cyphert, Holly, Guo, Shuangli, Liu, Jin-Hua, Guo, Min, Bass, Joseph, Magnuson, Mark A., Wright, Christopher, Stein, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2017
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652607/
https://www.ncbi.nlm.nih.gov/pubmed/28705881
http://dx.doi.org/10.2337/db16-1516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652607/
https://www.ncbi.nlm.nih.gov/pubmed/28705881
http://dx.doi.org/10.2337/db16-1516

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