Pancreatic β-Cell–Derived IP-10/CXCL10 Isletokine Mediates Early Loss of Graft Function in Islet Cell Transplantation

Pancreatic islets produce and secrete cytokines and chemokines in response to inflammatory and metabolic stress. The physiological role of these “isletokines” in health and disease is largely unknown. We observed that islets release multiple inflammatory mediators in patients undergoing islet transp...

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Detalles Bibliográficos
Autores principales: Yoshimatsu, Gumpei, Kunnathodi, Faisal, Saravanan, Prathab Balaji, Shahbazov, Rauf, Chang, Charles, Darden, Carly M., Zurawski, Sandra, Boyuk, Gulbahar, Kanak, Mazhar A., Levy, Marlon F., Naziruddin, Bashoo, Lawrence, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2017
Materias:
Immunology and Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652609/
https://www.ncbi.nlm.nih.gov/pubmed/28855240
http://dx.doi.org/10.2337/db17-0578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652609/
https://www.ncbi.nlm.nih.gov/pubmed/28855240
http://dx.doi.org/10.2337/db17-0578

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