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Hinokitiol up-regulates miR-494-3p to suppress BMI1 expression and inhibits self-renewal of breast cancer stem/progenitor cells

Hinokitiol (β-thujaplicin) is a tropolone-related compound that has anti-microbe, anti-inflammation, and anti-tumor effects. Cancer stem/progenitor cells (CSCs) are a subpopulation of cancer cells with tumor initiation, chemoresistant, and metastatic properties and have been considered the important...

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Detalles Bibliográficos
Autores principales: Chen, Shih-Ming, Wang, Bing-Yen, Lee, Che-Hsin, Lee, Hsueh-Te, Li, Jung-Jung, Hong, Guan-Ci, Hung, Yu-Chieh, Chien, Peng-Ju, Chang, Che-Ying, Hsu, Li-Sung, Chang, Wen-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652685/
https://www.ncbi.nlm.nih.gov/pubmed/29100291
http://dx.doi.org/10.18632/oncotarget.18648