Novel tropolones induce the unfolded protein response pathway and apoptosis in multiple myeloma cells

Tropolones are small organic compounds with metal-directing moieties. Tropolones inhibit the proliferation of cancer cell lines, possibly through their effects on metalloenzymes such as select histone deacetylases (HDACs). Pan-HDAC inhibitors are therapeutically beneficial in the treatment of multip...

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Detalles Bibliográficos
Autores principales: Haney, Staci L., Allen, Cheryl, Varney, Michelle L., Dykstra, Kaitlyn M., Falcone, Eric R., Colligan, Sean H., Hu, Qiang, Aldridge, Alyssa M., Wright, Dennis L., Wiemer, Andrew J., Holstein, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652688/
https://www.ncbi.nlm.nih.gov/pubmed/29100294
http://dx.doi.org/10.18632/oncotarget.18543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652688/
https://www.ncbi.nlm.nih.gov/pubmed/29100294
http://dx.doi.org/10.18632/oncotarget.18543

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