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Novel tropolones induce the unfolded protein response pathway and apoptosis in multiple myeloma cells
Tropolones are small organic compounds with metal-directing moieties. Tropolones inhibit the proliferation of cancer cell lines, possibly through their effects on metalloenzymes such as select histone deacetylases (HDACs). Pan-HDAC inhibitors are therapeutically beneficial in the treatment of multip...
Autores principales: | Haney, Staci L., Allen, Cheryl, Varney, Michelle L., Dykstra, Kaitlyn M., Falcone, Eric R., Colligan, Sean H., Hu, Qiang, Aldridge, Alyssa M., Wright, Dennis L., Wiemer, Andrew J., Holstein, Sarah A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652688/ https://www.ncbi.nlm.nih.gov/pubmed/29100294 http://dx.doi.org/10.18632/oncotarget.18543 |
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