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Integration of genomic, transcriptomic and functional profiles of aggressive osteosarcomas across multiple species

In complex, highly unstable genomes such as in osteosarcoma, targeting aberrant checkpoint processes (metabolic, cell cycle or immune) may prove more successful than targeting specific kinase or growth factor signaling pathways. Here, we establish a comparative oncology approach characterizing the m...

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Detalles Bibliográficos
Autores principales: Davis, Lara E., Jeng, Sophia, Svalina, Matthew N., Huang, Elaine, Pittsenbarger, Janét, Cantor, Emma L., Berlow, Noah, Seguin, Bernard, Mansoor, Atiya, McWeeney, Shannon K., Keller, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652702/
https://www.ncbi.nlm.nih.gov/pubmed/29100308
http://dx.doi.org/10.18632/oncotarget.19532