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Integration of genomic, transcriptomic and functional profiles of aggressive osteosarcomas across multiple species
In complex, highly unstable genomes such as in osteosarcoma, targeting aberrant checkpoint processes (metabolic, cell cycle or immune) may prove more successful than targeting specific kinase or growth factor signaling pathways. Here, we establish a comparative oncology approach characterizing the m...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652702/ https://www.ncbi.nlm.nih.gov/pubmed/29100308 http://dx.doi.org/10.18632/oncotarget.19532 |