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Molecular signatures reflecting microenvironmental metabolism and chemotherapy-induced immunogenic cell death in colorectal liver metastases

BACKGROUND: Metastatic colorectal cancer (CRC) is associated with highly variable clinical outcome and response to therapy. The recently identified consensus molecular subtypes (CMS1-4) have prognostic and therapeutic implications in primary CRC, but whether these subtypes are valid for metastatic d...

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Detalles Bibliográficos
Autores principales: Østrup, Olga, Dagenborg, Vegar Johansen, Rødland, Einar Andreas, Skarpeteig, Veronica, Silwal-Pandit, Laxmi, Grzyb, Krzysztof, Berstad, Audun Elnæs, Fretland, Åsmund Avdem, Mælandsmo, Gunhild Mari, Børresen-Dale, Anne-Lise, Ree, Anne Hansen, Edwin, Bjørn, Nygaard, Vigdis, Flatmark, Kjersti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652706/
https://www.ncbi.nlm.nih.gov/pubmed/29100312
http://dx.doi.org/10.18632/oncotarget.19350