The 30 kb deletion in the APOBEC3 cluster decreases APOBEC3A and APOBEC3B expression and creates a transcriptionally active hybrid gene but does not associate with breast cancer in the European population

APOBEC3B, in addition to other members of the APOBEC3 gene family, has recently been intensively studied due to its identification as a gene whose activation in cancer is responsible for a specific pattern of massively occurring somatic mutations. It was recently shown that a common large deletion i...

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Detalles Bibliográficos
Autores principales: Klonowska, Katarzyna, Kluzniak, Wojciech, Rusak, Bogna, Jakubowska, Anna, Ratajska, Magdalena, Krawczynska, Natalia, Vasilevska, Danuta, Czubak, Karol, Wojciechowska, Marzena, Cybulski, Cezary, Lubinski, Jan, Kozlowski, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652711/
https://www.ncbi.nlm.nih.gov/pubmed/29100317
http://dx.doi.org/10.18632/oncotarget.19400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652711/
https://www.ncbi.nlm.nih.gov/pubmed/29100317
http://dx.doi.org/10.18632/oncotarget.19400

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