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Suppression of pancreatic adenocarcinoma upregulated factor (PAUF) increases the sensitivity of pancreatic cancer to gemcitabine and 5FU, and inhibits the formation of pancreatic cancer stem like cells

Pancreatic cancer stem cells (CSCs) play a crucial role in tumorigenesis and chemoresistance of pancreatic ductal adenocarcinoma. Pancreatic adenocarcinoma up-regulated factor (PAUF), a novel secretory protein, has been shown to contribute to cancer progression and metastasis. Because the clinical r...

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Detalles Bibliográficos
Autores principales: Cho, Jae Hee, Kim, Sun A., Park, Soo Been, Kim, Hee Man, Song, Si Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652714/
https://www.ncbi.nlm.nih.gov/pubmed/29100320
http://dx.doi.org/10.18632/oncotarget.19458