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Fiber-modified hexon-chimeric oncolytic adenovirus targeting cancer associated fibroblasts inhibits tumor growth in gastric carcinoma

OBJECTIVE: To evaluate the effects of fiber-modified hexon-chimeric recombinant oncolytic adenovirus targeting cancer associated fibroblasts (CAFs) on the gastric CAFs and the transplantation tumor mice model of gastric carcinoma (GC). RESULTS: Compared with BJ cells and GPFs, the reproduction and i...

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Detalles Bibliográficos
Autores principales: Pang, Tao, Wang, Xinghua, Gao, Jun, Chen, Wei, Shen, Xiao Jun, Nie, Ming Ming, Luo, Tianhang, Yin, Kai, Fang, Guoen, Wang, Kai Xuan, Xue, Xu Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652720/
https://www.ncbi.nlm.nih.gov/pubmed/29100326
http://dx.doi.org/10.18632/oncotarget.20273