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Adenovirus-mediated decorin expression induces cancer cell death through activation of p53 and mitochondrial apoptosis
Decorin (DCN) is a small leucine-rich proteoglycan that plays an important role in the regulation of apoptosis, proliferation, intercellular contact, and cell migration. Here we have investigated the detailed mechanism of apoptotic cell death induced by DCN expression. A marked increase in cytotoxic...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652734/ https://www.ncbi.nlm.nih.gov/pubmed/29100340 http://dx.doi.org/10.18632/oncotarget.20800 |