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Alu hypomethylation and MGMT hypermethylation in serum as biomarkers of glioma

In order to improve prognosis of glioma patients, better tools are required for early diagnosis and treatment. Serum cell-free DNA methylation levels of Alu, MGMT, P16, RASSF1A from 124 glioma patients and 58 healthy controls were detected by the bisulfite sequencing. The median methylation level of...

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Detalles Bibliográficos
Autores principales: Gong, Mingjie, Shi, Wei, Qi, Jing, Shao, Guoping, Shi, Zhenghua, Wang, Junxiang, Chen, Jian, Chu, Rongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652743/
https://www.ncbi.nlm.nih.gov/pubmed/29100349
http://dx.doi.org/10.18632/oncotarget.20012