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Glyoxalase 1 copy number variation in patients with well differentiated gastro-entero-pancreatic neuroendocrine tumours (GEP-NET)

BACKGROUND: The glyoxalase-1 gene (GLO1) is a hotspot for copy-number variation (CNV) in human genomes. Increased GLO1 copy-number is associated with multidrug resistance in tumour chemotherapy, but prevalence of GLO1 CNV in gastro-entero-pancreatic neuroendocrine tumours (GEP-NET) is unknown. METHO...

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Detalles Bibliográficos
Autores principales: Xue, Mingzhan, Shafie, Alaa, Qaiser, Talha, Rajpoot, Nasir M., Kaltsas, Gregory, James, Sean, Gopalakrishnan, Kishore, Fisk, Adrian, Dimitriadis, Georgios K., Grammatopoulos, Dimitris K., Rabbani, Naila, Thornalley, Paul J., Weickert, Martin O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652755/
https://www.ncbi.nlm.nih.gov/pubmed/29100361
http://dx.doi.org/10.18632/oncotarget.20290