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Targeting CXCR4 reverts the suppressive activity of T-regulatory cells in renal cancer

With the intent to identify biomarkers in renal cell carcinoma (RCC) the functional status of T-regulatory cells (Tregs) was investigated in primary RCC. Tregs were isolated from tumoral-(TT), peritumoral tissue-(PT) and peripheral blood-(PB) of 42 primary RCC patients and function evaluated through...

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Detalles Bibliográficos
Autores principales: Santagata, Sara, Napolitano, Maria, D'Alterio, Crescenzo, Desicato, Sonia, Maro, Salvatore Di, Marinelli, Luciana, Fragale, Alessandra, Buoncervello, Maria, Persico, Francesco, Gabriele, Lucia, Novellino, Ettore, Longo, Nicola, Pignata, Sandro, Perdonà, Sisto, Scala, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652768/
https://www.ncbi.nlm.nih.gov/pubmed/29100374
http://dx.doi.org/10.18632/oncotarget.20363