Cargando…

SHARPIN stabilizes estrogen receptor α and promotes breast cancer cell proliferation

Estrogen receptor α is expressed in the majority of breast cancers and promotes estrogen-dependent cancer progression. In our study, we identified the novel E3 ubiquitin ligase SHARPIN function to facilitate ERα signaling. SHARPIN is highly expressed in human breast cancer and correlates with ERα pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhuang, Ting, Yu, Sifan, Zhang, Lichen, Yang, Huijie, Li, Xin, Hou, Yingxiang, Liu, Zhenhua, Shi, Yuanyuan, Wang, Weilong, Yu, Na, Li, Anqi, Li, Xuefeng, Li, Xiumin, Niu, Gang, Xu, Juntao, Hasni, Muhammad Sharif, Mu, Kun, Wang, Hui, Zhu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652769/
https://www.ncbi.nlm.nih.gov/pubmed/29100376
http://dx.doi.org/10.18632/oncotarget.20368