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Sitagliptin attenuates high glucose-induced alterations in migration, proliferation, calcification and apoptosis of vascular smooth muscle cells through ERK1/2 signal pathway
BACKGROUND/AIMS: This study investigated the effects of sitagliptin on migration, proliferation, calcification and apoptosis of vascular smooth muscle cells (VSMCs) under high glucose (HG) conditions. METHODS: VSMCs were isolated from the thoracic aorta of Sprague Dawley rats. The cultured VSMCs wer...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652771/ https://www.ncbi.nlm.nih.gov/pubmed/29100378 http://dx.doi.org/10.18632/oncotarget.20417 |