Gambogic acid inhibits thioredoxin activity and induces ROS-mediated cell death in castration-resistant prostate cancer

Advanced prostate cancer (PrCa) is treated with androgen deprivation therapy, and although there is usually a significant initial response, recurrence arises as castrate resistant prostate cancer (CRPC). New approaches are needed to treat this genetically heterogeneous, phenotypically plastic diseas...

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Detalles Bibliográficos
Autores principales: Pan, Hong, Jansson, Keith H., Beshiri, Michael L., Yin, JuanJuan, Fang, Lei, Agarwal, Supreet, Nguyen, Holly, Corey, Eva, Zhang, Ying, Liu, Jie, Fan, HuiTing, Lin, HongSheng, Kelly, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652772/
https://www.ncbi.nlm.nih.gov/pubmed/29100379
http://dx.doi.org/10.18632/oncotarget.20424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652772/
https://www.ncbi.nlm.nih.gov/pubmed/29100379
http://dx.doi.org/10.18632/oncotarget.20424

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