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Gambogic acid inhibits thioredoxin activity and induces ROS-mediated cell death in castration-resistant prostate cancer

Advanced prostate cancer (PrCa) is treated with androgen deprivation therapy, and although there is usually a significant initial response, recurrence arises as castrate resistant prostate cancer (CRPC). New approaches are needed to treat this genetically heterogeneous, phenotypically plastic diseas...

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Detalles Bibliográficos
Autores principales:	Pan, Hong, Jansson, Keith H., Beshiri, Michael L., Yin, JuanJuan, Fang, Lei, Agarwal, Supreet, Nguyen, Holly, Corey, Eva, Zhang, Ying, Liu, Jie, Fan, HuiTing, Lin, HongSheng, Kelly, Kathleen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652772/ https://www.ncbi.nlm.nih.gov/pubmed/29100379 http://dx.doi.org/10.18632/oncotarget.20424

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