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Histone deacetylase inhibitors vorinostat and panobinostat induce G1 cell cycle arrest and apoptosis in multidrug resistant sarcoma cell lines

Synovial sarcoma and high grade chondrosarcoma are characterized by their lack of response to conventional cytotoxic chemotherapy, the tendency to develop lung metastases, and low survival rates. Research within the field prioritizes the development and expansion of new treatment options for dealing...

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Detalles Bibliográficos
Autores principales: Bernhart, Eva, Stuendl, Nicole, Kaltenegger, Heike, Windpassinger, Christian, Donohue, Nicholas, Leithner, Andreas, Lohberger, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652778/
https://www.ncbi.nlm.nih.gov/pubmed/29100385
http://dx.doi.org/10.18632/oncotarget.20460